I myself have not used this treatment but two of my daughters are on it. The difference in there well being is phenomenal. There health and everyday activity has improved beyond my expectations. There no longer taking prescription drugs or buying over the counter medicines. I highly recommend the pellet treatment for cell and hormone replacement. Dr. Afia Naqvi and her staff are awesome, well educated and professional. Thank you Dr. Naqvi for giving my daughters lives back to them. A Happy Mother!!!!*